生化学と分析生化学

概要

Traditional Medicine Based Drug Development

Pathirage Kamal Perera

Currently few of traditional medicines have been developed by blending basic sciences and technologies up to the clinical usage. In future standard traditional medicine based botanical therapeutics will be important in biomedicine developments due to economic background in most parts of the world. Today there are many basic experimental research have being doing for plant based materials. But very limited data can be founded for evidence based use of those experimented plant materials in clinical setup. Therefore this is the high time for develop effective evidence based traditional medicine system in the world. This can be done by evaluating traditional medicine remedies for their pharmacodynamics, pharmacokinetics, stability, shelf life and toxicity par with current standards. Challenge of reproducibility and consistency of herbal remedies can be achieved by developing standard assay markers and chemiinformatic approaches. Further conventional concepts of clinical research design methods may not be adequate when evaluating and conducting clinical trials for traditional medicine. Therefore needs to identifying traditional medicine concepts and develop research strategies for achieve full benefits of these medicine systems. Further there is need to develop and validate a range of parameters applicable to modern and traditional medicines in the light of basic sciences like biochemistry and molecular biology.