ジャーナル・オブ・ファーマコビジランス

概要

Methylphenidate-Induced Acute Dystonic Reaction: A case report

Ayse Erdogan and Hakan Erdogan

Dystonia is a syndrome characterized by sustained muscle contractions frequently causing twisting and repetitive movements or abnormal postures. Dystonic reactions may be a complication of many drugs such as antipsychotics, anti-emetics and antidepressants. This report presents a 4-year-old healthy boy who was admitted to an emergency department with acute dystonia following the ingestion of methylphenidate, a stimulant pharmalogical agent used for the treatment for attention-deficit hyperactivity disorder. In conclusion, this report suggests that methylphenidate increase dopaminergic transmission can also trigger dystonic reaction in at healthy child.