生化学と分析生化学

概要

Impact of Soy Bean on Thyroid Hormones of Albino Rats

Nwachoko N and Jack IR

Soy foods are traditional staples of Asian diets. Soy bean and thyroid health have focused on one specific category of nutrient-Isoflavones found in soy bean. This study examined the impact of soy bean on thyroid hormones which are thyroid stimulating hormone (TSH), tri-iodothyronine (T3) and thyroxine (T4) in albino rats. This was carried out in two phases. The rats were grouped in both phases of four groups, three rats in each group. The first phase was by feeding the animals at varying percentage (30, 50 and 70) for two weeks, while the second phase was by administration of soybean extract at (500, 1000 and 2000 mg/kg) respectively for same duration. The result obtained showed that thyroid hormones values for the fed groups were not significantly (p<0.05) different with that of the control group. Also the result obtained for phase two showed that thyroid hormones values of the treated groups were not significantly (p<0.05) different with that of the control group. The result for both phases showed that soy bean has no significant impact on the thyroid hormones levels of albino rates.