ジャーナル・オブ・ファーマコビジランス

概要

Cutaneous Adverse Drug Reaction with Ofloxacin

Inderpal Kaur, Suneet Jindal and Inderpal Singh Grover

Drug-induced cutaneous adverse effects are major health problem. Its predominant forms include maculopapular rash, Stevens - Johnson syndrome, toxic epidermal necrolysis, fixed drug eruption and urticaria. Ofloxacin is a fluoroquinolone and is widely used for the treatment of infective diarrhoea as a single drug or in combination with ornidazole. Earlier one case of toxic epidermal necrolysis has been reported with the use of ofloxacin. Here we report a case of mucocutaneous maculopapular rash with oral ofloxacin.