生化学と分析生化学

概要

COVID-19: Review on the Biochemical Perspective of the Structural and Non-structural Proteins Involved in SARS-CoV-2 Corona Virus

Soumya V. Menon

A novel member of human SARS-CoV-2 that has recently emerged in Wuhan, China, is now formally named as SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). This is a unique strain of RNA viruses that have not been previously observed in humans. The virus has wide host adaptability and is capable of causing severe diseases in humans, masked palm civets, mice, dogs, cats, camels, pigs, chickens, and bats. The SARS-CoV-2 typically causes respiratory and gastrointestinal sickness in both humans and animals. The main objective of this review is to address the important biochemical aspects of SARS-CoV-2 corona virus. There is a critical need to study the structural and non-structural proteins involved in this virus to understand and support the clinical, biochemical and structural studies to combat the pandemic occurrence all over the world by SARS-CoV-2. The review also gives a comprehensive view of the various analytical techniques used to study the corona virus such as size exclusion chromatography, circular dichroic spectroscopy, and Multiage Light Scattering and micro array methods.