生化学と分析生化学

概要

Cancer Cell Growth - A Mini Review Part-2: Crabtree Effect, Pasteur Effect, Pyruvate Kinasetrient

Koyunoglu C

The objective of this work is to address the mechanism how cancer cell growth. Current study has actually featured the metabolic versatility significance in both in vivo and cultured cells. As an example, development in the extreme subcutaneous area in mice environment or glucose deprivation, generates a careful impact for KRAS anomalies in cancer cells of colon. For circumstances, altered KRAS low glucose conditions rendered cells tolerant. Likewise, in culture, cancer cells can reorganize their metabolic process making up for the loss of either glutamine or glucose, commonly making use of a nutrient filling metabolite pools usually be provided by the other. In this part of mini review Crabtree Effect, Pasteur Effect, Pyruvate Kinasetrient terms summarized.