老年学と老年医学の研究

概要

Use of Drugs Prolonging QT Interval in Patients at the Time of Admission to Geriatric Department

Peter Mikus ,Stefan Krajcik *,Peter Ciutti

The usage of drugs prolonging QT interval is common issue in old age. They were used by 67.5% of patients being admitted to geriatric department. Use of these drugs was associated with a higher 3-month mortality rate (36.6% versus 16.7%). This mortality rate was significantly higher in patients using 3 and more of these drugs. Patients, who did not survive 3 months used QT interval prolonging drugs significantly more often (83.3 % versus 67. 5%).The most frequently used group of drugs were diuretics used by 36% of patients. The most often used drug was furosemide, used by 32.5% of patients. The second most used group were antipsychotic drugs which were used by 24% of patients. The second most frequently used medicament was pantoprazole used by 22.5% patients. Antidepressants were used by 15.4% of patients. The most often used antidepressant was citalopram, which belongs to drugs with a high risk of QT interval prolongation. It was used by 6.1% of patients.