臨床医学ジャーナル

概要

Treatment of Temporal Lobe Epilepsy with Stem Cells

Mihaela Badea

Epilepsy affects 65 million individuals worldwide, with over 5.5 million people in India alone suffering from the condition. Epilepsy is defined by the occurrence of seizures that are unpredictable due to an imbalance in excitatory and inhibitory activity between brain regions. Temporal Lobe Epilepsy (TLE) is one of the most well-known epilepsies, accounting for around 40 % of epilepsy patients. In TLE, an Initial Precipitating Injury (IPI) such as status epilepticus, stroke, head injury, febrile seizure, brain tumour, or encephalitis is usually detected, followed by a latent period of no seizure activity, and then the emergence of Spontaneous Recurrent Motor Seizures (SRMS).