ナノメディシンとナノテクノロジーのジャーナル

概要

Traditional Biocidal Replacement Viability of Microcrystalline Silver Chloride

Hemminger Z, Walsh P, Curtis R and Kristin Picardo

The antimicrobial effects of silver ions and silver chloride nanoparticles have been well established while the efficacy of microcrystalline silver chloride has been less studied. Certex-AM, a microcrystalline silver chloride product produced by Cerion, Rochester, NY, was tested for its antimicrobial properties as a possible replacement for traditional biocidal techniques used in water cooling towers. The minimum inhibitory concentration (MIC) of the compound was determined using a microtiter broth assay. The compound was found to have inhibitory effects on bacterial growth for all tested organisms at concentrations greater than 9 ppm. Additional testing simulating a water cooling system showed the effectiveness of reducing an established wild population at concentrations of 10 ppm of the microcrystalline silver chloride. Certex-AM was found to be a promising replacement for traditional biocides as well as for other applications. Introduction of effective antimicrobial compounds such as this could reduce the pathogenic risk to humans associated with water cooling towers.