細菌学および寄生虫学ジャーナル

概要

The Potential Activity of Hydroxychavicol against Pathogenic Bacteria

Jangala Jesonbabu, Navuru Spandana and Aruna lakshmi K

Hydroxychavicol isolated from Piper betle leaves, showed inhibitory activity against gastrointestinal pathogens. It exhibited inhibitory effect on the entire gastrointestinal pathogens tested (MICs of 200-400 ?g/ml) with an MBC, which was twofold greater than the inhibitory concentration. Hydroxychavicol exhibited concentration dependent killing of Staphylococcus aureus and Escherichia coli to 4 x MIC, that the hydroxychavicol would be a useful compound for the development of antibacterial agents against gastro intestinal pathogens and has great potential for use in treatment of gastrointestinal infections.