血液疾患と輸血ジャーナル

概要

Risk Stratification of Patients with Myelofibrosis in the HEMORIO: A Retrospective Study

Ana Maria Mach Queiroz*, Luiz Amorim Filho, Renata Cravo Queiroz

Background: Myelofibrosis patients may be classified into risk categories that were developed using a prognostic scoring system which includes several factors. The objective of this article is to obtain knowledge about the riskclassification distribution of myelofibrosis in a high complexity unit in the period of 2019.

Methods: This is an observational, descriptive and retrospective study with a quantitative approach in which 17 medical records of patients diagnosed with primary myelofibrosis were assessed.

Results: The average age at diagnosis was around the sixth and seventh decades of life. An improvement in the risk classification of the studied patients is observed, demonstrating a more effective treatment. In the evaluation of presence of constitutional symptoms the results have shown that four patients had weight loss, three had fever, seven had sweating, seven had fatigue, five had constant abdominal pain, six had pruritus and eight had some type of bone pain. No early satiety was reported by any patient.

Conclusions: Myelofibrosis patients monitored in the HEMORIO are mostly classified as intermediate risk individuals. Analyses of disease characteristics are essential for a better understanding and definition of strategies to its management.