ファーマシューティカ アナリティカ アクタ

概要

Rapid and Selective LC method for estimation of Duloxitine Hydrochloride

Pushpa Kumari K

The Duloxitine Hydrochloride was estimated by using a HPLC method. It was separated on a Waters symmetry C8 HPLC column (250 × 4.6 mm, 5μ) by passing mobile phase at a flow rate of 1.0 ml/min and the solution was monitored at a wavelength of 288nm. The retention time of the duloxitine was found to be 7.39 min. The developed method was validated according to ICH guidelines. The developed method was accurate, precise and linear. This method can be successfully applied in quality control laboratories for routine analysis of duloxitine in pharmaceutical formulations.