インデックス付き
- Jゲートを開く
- Genamics JournalSeek
- アカデミックキー
- ジャーナル目次
- サイテファクター
- ウルリッヒの定期刊行物ディレクトリ
- Global Online Research in Agriculture (AGORA) へのアクセス
- 電子ジャーナルライブラリ
- 国際農業生物科学センター (CABI)
- レフシーク
- 研究ジャーナル索引作成ディレクトリ (DRJI)
- ハムダード大学
- エブスコ アリゾナ州
- OCLC-WorldCat
- 学者の舵取り
- SWBオンラインカタログ
- 仮想生物学図書館 (vifabio)
- パブロン
- ジュネーブ医学教育研究財団
- ユーロパブ
- Google スカラー
このページをシェアする
ジャーナルチラシ
概要
Phytochemical Analysis and Antibacterial and Cytotoxic Properties of Barleria lupulina Lindl. Extracts
Reshma Kumari and Ramesh Chandra Dubey
The ethanolic and aqueous extracts of Barleria lupulina leaves displayed antibacterial activity against five human bacterial pathogens viz., Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Salmonella typhi Klebsiella pneumoniae. The ethanolic extract was more inhibitory than the aqueous extract against all the test pathogens, which caused the maximum growth inhibition of P. aeruginosa at 100% concentration. In contrast, aqueous extract did not inhibit the growth of any bacterial pathogens. MIC of ethanolic extract was 2.5 mg/mL against E. coli, S. aureus and P. aeruginosa, and 10.0 mg/mL against S. typhi and K. pneumonia. GC-MS analysis displayed the presence of twelve phytochemical compounds among which benzofuranon, hexadecanoic acid, ethyl 9,12,15-octadecatrienoate, and 3,7,11,15-tetramethyl-2-hexadecanoic acid were the most prominent ones. These extracts also displayed cytopathic effects against HepG2 cell line performed by employing the 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) and neutral red uptake (NRU) assay which demonstrated the varying levels of cell death of HepG2 cells by ethanolic extract. The ethanolic extract of B. lupulina bears a significant amount of phytochemical compounds that pose antibacterial as well as anti-cancerous properties.