水産養殖研究開発ジャーナル

概要

Marine Antimicrobial Peptides (AMPs) - A Promising Natural Alternative to Antibiotics

Pani Prasad Kurcheti*, Abisha Juliet Mary, Dhayanath M

An unsolved and growing problem nowadays is known to be an antimicrobial resistance which have created a worldwide health crisis. This concern leads to seek new or alternative antimicrobial drugs. Antimicrobial peptides and biotechnology together possess a promising future in regards of this issue as AMPs are natural peptides which serve its purpose as therapeutic and antimicrobials. Even though, these biomolecules are believed to act on bacterial membranes primarily, on-going researches are suggesting that the activity of the AMP might be broader. Till date, more than 1, 000 AMPs have been isolated, and the number is rapidly growing which were reported in antimicrobial peptide databases. Initially, these molecules were isolated and characterized from terrestrial environments. Recently, the focus was shifting towards marine ecology due to their immense diversity of organisms and microorganisms that interacts with each other. This article deals with the marine antimicrobial peptides with special attraction on its antimicrobial properties.