微生物および生化学技術ジャーナル

概要

Intra-Family and Inter-Family Comparisons for Viral Susceptibility to Heat Inactivation

Raymond W Nims and Mark Plavsic

A systematic review of the viral heat inactivation literature for data compatible with modeling using the decimal reduction value/z value approach as well as a new approach based on the power function relationship between decimal reduction value and inactivation temperature is presented. The review has enabled us to conduct quantitative intra-family and inter-family comparisons for various heat inactivation characteristics for viruses, including z value, temperature in°C for 1 log10 and for 4 log10 inactivation in 30 seconds. The parvoviridae family is confirmed to be the most heat resistant of the various virus families for which data were analyzed.