薬物疫学と医薬品の安全性の進歩

概要

High Active Anti-retroviral Therapy for HIV/AIDS, Progresses and Drawback

Da-Yong Luand Ting-Ren Lu

AIDS (acquired immune deficient syndrome) is a human infectious disease. AIDS patients, if not be treated, commonly suffer a gradual loss of human immune-defensive functions and finally die of infectious complications within 2 years after AIDS symptoms occur in patients. AIDS patients can be treated with a series of anti-viral drugs to decrease the virus-load and slow the pace of occurrence AIDS and ameliorate the symptoms of immune deficient and prolong the life-spans of patients by high active anti-retroviral therapy (HAART). Even though HAART is very effective, HIV/AIDS patients cannot be cured by HAART. And there are a lot of precautious for this therapy. There are a plethora of reasons behind these phenomena. In this review, we will detail address this problem and try to give new directions.