老年学と老年医学の研究

概要

Geriatric Traumatic Brain Injury: Relationship to Dementia and Neurodegenerative Disease

Edward H Tobe*

The author explores a hypothesis that the elderly are vulnerable to traumatic brain injury (TBI) precipitating or accelerating dementia or neurodegenerative diseases due to intracellular changes in physiological resilience. Bearing in mind the global human experience, biologic resilience is vulnerable to a vast number of human created and natural conditions. Respectfully, this paper focuses on the role of certain cultural biases, aging, genetic factors, synaptic efficacy, and intracellular enzymatic balance. Clinical vigilance enables diagnosis and treatment leading to improved quality of life.