新生児生物学ジャーナル

概要

Evaluation of Cardiac Reserve Function in Gestational Hypertension

Fengzhi You, Lingling Weng , Yi Zhang , Guomei Cheng, Qi Qin , Shihong Cui, Xiaoli Guo , Ruili Wang , Wei Chen1 and Linbin Jia

Objective: Explore the cardiac reserve function in gestational hypertension,in order to provide a basis for the prevention and early treatment of pregnancy with hypertension disease and reduce the maternal and infant complications.

Methods: We collected the related information of 112 pregnant women with gestational hypertension and 224 normal pregnant women who do perinatal care in Department of Women’s Health Care Division of Third Affiliated Hospital of Zhengzhou University from January 2009 to December 2012. We acquired the phonocardiogram with resting state and take the ratio of S1/S2(first heart sound maximum amplitude ratio of the second heart sound maximum amplitude of S1 and S2)D/S (diastolicto systolic duration) HR(heart rate) as the indicators of cardiac reserve function.

Results: The comparison of the indicators between pregnant women with gestational hypertension and normal pregnant women show that S1/S2 between two groups have no significant difference while D/S and HR are significantly different; D/S values at 12?27+6weeks ≥28 weeks in the two groups are significantly different (p<0.05), while D/S values have no significant difference when the gestational age ≤11+6 weeks.

Conclusion: The cardiac reserve function of gestational hypertension pregnant women are significantly lower than the normal pregnant women. The cardiac reserve function of gestational hypertension pregnant women reduces with gestational age.