Saurav Deka, Betina Chandolia, Farah Iram, Niveditha Hariharan, Aparajita Dubey*
WHO declared the coronavirus outbreak as a global pandemic in March 2020, which has affected 220 countries across the globe and territories, with 169,597,415 confirmed cases and 3,530,582 deaths reported to date. SARSCoV- 2 vaccines are the best bet to control the pandemic and restore normalcy. Two of the mRNA vaccines got initial Emergency Use Authorization (EUA) from the US Food and Drug Administration (FDA), followed by the Advisory Committee on Immunization Practice (ACIP) initiative of publishing new guidance on vaccine priorities. Since millions of people are getting vaccinated, reports of temporary side effects and rare allergic reactions raised some troubling questions. Although there is no doubt related to the safety and efficacy of the current vaccines, the risk for the severe reaction gets entirely outweighed by the protection offered against the deadly coronavirus. This review article highlights upon the development of COVID-19 vaccines, their possible side effects, and management strategies.