口腔の健康と歯の管理

概要

Comparative Clinical, Radiographical and Biochemical Evaluation of Autogenous Bone Graft in Periodontal Infrabony Defects: A Randomized Clinical Trial

Sanjeet Gill, Nymphea Pandit, Praveen Sharma, AB Pant

Background: The aim of this clinical study was to evaluate and compare the efficacy of autogenous bone graft procured with the help of bone scraper over open flap debridement in treatment of human periodontal infrabony defects.

Materials and method: 30 infrabony defects were chosen for the study, 15 sites were treated with autogenous bone graft, obtained with the help of scraper and in the rest 15 sites only open flap debridement was performed. The clinical and radiographic parameters were analysed at baseline, 3 months and 6 months using student’s t-test. The bone obtained with the help of bone scraper was also analysed biochemically to determine its particle size and Zeta Potential.

Results: At 6 months, there was a significant improvement in clinical attachment level, defect fill and defect resolution in most of the test sites as compared to control. The Zeta potential values showed that autogenous bone thus procured with bone scraper has potential osteogenic activity in the grafted site.

Conclusion: Autogenous bone grafts led to highly significant gain in clinical attachment level, defect fill and defect resolution as compared to open flap debridement.