現代の化学と応用

概要

Commentary Note on Pharmacodynamics

Sathvik Arava

Pharmacodynamics describes the relationship between the concentration of an active ingredient at its site of action (usually a receptor) and the effect of the corresponding active ingredient. Administration of a combination of drugs may change this dose-response relationship. Clinically relevant examples of such interactions. Studies of PD interactions have assumed that the underlying PK interactions will inevitably lead to subsequent changes in clinical efficacy.