腫瘍研究とレポートのジャーナル

概要

Chronic Myelogenous Leukemia (CML): Cancer of Bone Marrow

Priya Pandey

Tumour is uncontrollable growth of abnormal cells which leads to damage of self cells. Tumour in the body leads to formation of cancer and different types of cancer are named on the basis of body part the tumour cells target or originate from, like brain cancer mostly affects brain. Similarly, chronic myelogenous leukemia is also a type of cancer that occurs in bone marrow of the body. Bone marrow is present inside bones and it is spongy tissue which forms blood cells. Chronic Myelogenous Leukemia (CML) affects blood cells and bone marrow. In this condition body forms a lot of White Blood Cells (WBCs) and it takes form of Leukemia as myeloid cells present in bone marrow increases abnormally and rapidly and later on all these cells gets accumulated in the blood [1-3]. This condition usually occurs in elderly or older people and occurs due to mutations in genes of blood cells. Function of normal bone marrow is to produce red blood cells (which carries oxygen to other part of the body) and white blood cells (to fight against foreign matter) and platelets (To prevent clotting) but when CML occurs, bone marrow produces lot of white blood cells than other cells and later on these cells leads to formation of myeloblasts which gets accumulated in the bloodstream. Excessive growth of these myeloblasts leads to lackage of red blood cells and in result Anemia occurs