薬物疫学と医薬品の安全性の進歩

概要

Cardiovascular Medicine Safety Profile Evaluation among Urban Private Hospitals

Fredy IC, Palatty PL, Iqbal PT, Manikandan TV and Srinivasan R

The pharmacovigilance is on-going, mandatory process among medical college hospitals. The private hospitals organization is prioritized and structured differently. Regular efficacy and safety evaluations are not conducted as academic research but occur by default in teaching hospitals. This study investigated and collected adverse drug reactions in this site and contrasted with literature from existing studies to draw comparisons and appropriate interventions.
This was a cross sectional observational study design using conventional ADR form from Central Drugs Standard Control Organization and checklist of cardiovascular medicine specific adverse reactions which was administered for data collection after necessary formalities for patient recruitment. There were statistically significant differences in total number of cardiovascular medications prescribed, the common cardiovascular medicines used, common concomitant medicine prescribed. The ADR profile showed commonly mild and moderate severity with low incidence of severe adverse event.
The adverse reaction profile did have large number of reactions but in the milder range. The cautious prescribing of large number of medicines with low intensity ADRs indicates the discharge of cautious responsibility due to direct liability and awareness. Peer misdemeanors among small circle of professionals would have severe repercussions on their clientele.