生物学と医学

概要

Biochemical alteration of methanolic extract of Amaranthus spinosus on liver of Sprague Dawley rats

*Gul T, Singh K, Srivastava A, Ahirwar V

Amaranthus spinosus (spiny amaranth) is a tropical plant belonging to the family Amaranthaceae and is used widely as a vegetable and medicinal plant. The present study is carried out to investigate the biochemical role of methanolic extract of Amaranthus spinosus on liver of Sprague Dawley rats. Female albino rats were divided into two groups: one group served as control which was fed on normal diet, the second group served as experimental which receives a dose level of 250 mg/kg of methanolic extract of Amaranthus spinosus plant. Protein concentration was estimated in liver homogenate using the Lowry method (1951) with bovine serum albumin (BSA) as standard. Also, glycogen concentration was estimated in tested organ by using Seifter method (1950). Results showed significant increase for both acute as well as chronic studies in protein and glycogen contents at 250 mg/kg dose level.