微生物および生化学技術ジャーナル

概要

Antifungal Activity of Silver Nanoparticles Produced from Fungus, Penicillium fellutanum at Different pH

Nida Tabassum Khan and Namra Jameel

Currently there are many approaches being engaged in the production of silver nanoparticles however these methods uses reducing agents such as sodium borohydride, hydrazine and organic passivators like thiourea, thiophenol, mercaptoacetate, etc. which are environmental pollutants and increases the overall cost of the process. Therefore biosynthesis of silver nanoparticle is now considered to be the most environmental friendly, cost effective method. The effect of different pH on the synthesis of silver nanoparticles was observed by altering the pH of the fungal filtrate using 0.1 N sodium hydroxide and 0.1 N hydrochloric acid. Rapid rate of silver nanoparticles were obtained at pH 8.0 at λmax of 440. Produced silver nanoparticles were effective antifungal agents against Candida albicans, Candida glabrata and Candida tropicalis.