ナノメディシンとナノテクノロジーのジャーナル

概要

An Examination of Photonic Nanoparticles' Potential for Causing Nanotoxicity in Cultivated Cells Invitro

Jie Shao

Although optical nanoparticles (NPs) have the potential to offer new diagnostic and therapeutic tools for human diseases, it is yet unknown how biocompatible and hazardous they are at the nanoscale. Here, for a test on nanotoxicity, we created a number of common NPs (such as gold nanospheres, gold nanorods, silver nanopheres, silver triangular nanoplates, and quantum dots) with various materials and surface chemical modifications. SRB assay was used to examine cell proliferation in the co-culture of cancer cells with NPs. It was discovered that a number of variables, including material choice, physical size/surface area, shape, and surface chemical property, were strongly connected with the toxicity of NPs. When used as probes in the disciplines of biology and medicine, this work has the potential to deliver consistent and organised information.