Andras Szeles, Nayef T El-Daher, Neil Lachant, Toufic A Rizk
The high degree of variability in clinical severity and presentation among patients infected with SARS-CoV-2 continues to be an ongoing challenge for physicians managing the disease. In addition to acute respiratory distress syndrome, multi-organ dysfunction and shock state, there are now well recognized pro-inflammatory, hypercoagulable and pro-thrombotic complications associated with this infection. Acute Limb Ischemia (ALI) in particular has been documented with increasing frequency during the course of the pandemic with variable management strategies and outcomes. Herein we review the current state of the literature as it pertains to the epidemiology, diagnosis and management of ALI in the context of SARS-CoV-2 infection.