膜科学技術ジャーナル

概要

A Biological Membrane's Transmembrane Helices

Henriette Kirstine Christensen

In biology, certain protein-protein interactions are vital not only in the creation of a stable quaternary structure, but also in transitory interactions like signal transmission and gene expression regulation. Despite the availability of whole genomes for some species, understanding the activities of many gene products necessitates the identification of relationships among the encoded proteins. In recent years, a range of ways to studying such interactions have been created, including the invention of the two-hybrid system in yeast. While the two-hybrid technique for soluble proteins is well known, assessing the interaction of integral membrane proteins is more challenging, and viable approaches have just recently developed.